Inversion polymorphisms and nucleotide variability in Drosophila
نویسندگان
چکیده
منابع مشابه
Effect of inversion polymorphism on the neutral nucleotide variability of linked chromosomal regions in Drosophila.
Recombination is a main factor determining nucleotide variability in different regions of the genome. Chromosomal inversions, which are ubiquitous in the genus Drosophila, are known to reduce and redistribute recombination, and thus their specific effect on nucleotide variation may be of major importance as an explanatory factor for levels of DNA variation. Here, we use the coalescent approach ...
متن کاملIn!ersion polymorphisms and nucleotide !ariability in Drosophila
Population genetic models of molecular variation usually assume that most genetic variability is neutral or nearly so (Kimura, 1983). However, even if most variability is neutral, patterns of polymorphism may be indirectly shaped by natural selection (Gillespie, 1997). Indeed, theoretical studies show that neutral variability linked to selected sites may be influenced by different types of natu...
متن کاملPopulation Genomics of Inversion Polymorphisms in Drosophila melanogaster
Chromosomal inversions have been an enduring interest of population geneticists since their discovery in Drosophila melanogaster. Numerous lines of evidence suggest powerful selective pressures govern the distributions of polymorphic inversions, and these observations have spurred the development of many explanatory models. However, due to a paucity of nucleotide data, little progress has been ...
متن کاملThe evolutionary history of Drosophila buzzatii. XXXV. Inversion polymorphism and nucleotide variability in different regions of the second chromosome.
Inversions are portions of a chromosome where the gene order is reversed relative to a standard reference orientation. Because of reduced levels of recombination in heterokaryotypes, inversions have a potentially important effect on patterns of nucleotide variability in those genomic regions close to, or included in, the inverted fragments. Here we report sequence variation at three anonymous r...
متن کاملLinkage disequilibrium analysis of chromosomal inversion polymorphisms of Drosophila.
The linkage disequilibrium pattern analysis is a method that allows one to detect present and past events of selection. We applied it to our data on the inversions of Drosophila mediopunctata and to published data of Drosophila subobscura, which are systems probably under complex modes of selection. The method gave meaningful results showing that it might be an excellent exploratory tool to ide...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genetical Research
سال: 2001
ISSN: 0016-6723,1469-5073
DOI: 10.1017/s0016672301004955